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Tenofovir disoproxil fumarate (TDF) belongs to the class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (NtRTIs), which block reverse transcriptase, an enzyme crucial to viral production within HIV-infected population. These are indicated around combination by having more antiretroviral agencies for the coarse of action of HIV-One nausea within adults. This indication is according to analyses of plasma HIV-One RNA levels & CD4 cell numbers around restricted studies of tenofovir inside coarse of action-naïve & professional assistance-had adults. No learn effects demonstrating a consequence of tenofovir in clinical progression of HIV.

Tenofovir is presently around late-stage clinical test for the coarse of action of hepatitis B.

Tenofovir was found across the collaborative search effort between Dr Antonin Holy at the Academy of Sciences of the Czech Republic (IOCB) in Prague, & Dr Erik DeClercq, Rega Institute for Medical Research, Katholic University, Belgium.

Tenofovir is marketed by Gilead Sciences with the marque Viread®. It was approved per U.S. Food and Drug Administration (FDA) on July Two, 2003. These are too available inside the fixed-dose combination using emtricitabine in a product with a marque Truvada®, approved in August Two, 2004 for when-the-day dosing. (Emtricitabine is marketed as a lone-compound product known as Emtriva®, likewise marketed by Gilead.) The fixed-dose triple combination of tenofovir, emtricitabine & efavirenz (Sustiva®, marketed by Bristol-Myers Squibb) is in development.

Viread
Tenofovir disoproxil fumarate. Product information for US residents and healthcare professionals, including news, FAQs, and information about trials.

DrugDigest: Viread (Tenofovir)
Information from DrugDigest on dosage, usage, side effects, interactions, and drug comparisons including generics when available.

Tenofovir Disoproxil Fumarate
Full prescribing information from RxList.